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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDS5B
All Species:
22.73
Human Site:
S1257
Identified Species:
41.67
UniProt:
Q9NTI5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NTI5
NP_055847.1
1447
164667
S1257
R
K
R
G
H
T
A
S
E
S
D
E
Q
Q
W
Chimpanzee
Pan troglodytes
XP_509623
1487
169149
S1297
R
K
R
G
H
T
A
S
E
S
D
E
Q
Q
W
Rhesus Macaque
Macaca mulatta
XP_001118201
1528
173307
S1337
R
K
R
G
H
T
A
S
E
S
D
E
Q
Q
W
Dog
Lupus familis
XP_543139
1623
183240
S1432
R
K
R
G
H
T
A
S
E
S
D
E
Q
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
Q4VA53
1446
164401
S1257
R
G
R
T
A
S
D
S
D
E
Q
Q
W
P
E
Rat
Rattus norvegicus
Q6TRW4
1447
164441
S1257
R
K
R
G
H
A
A
S
E
S
E
E
Q
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509617
1452
165101
S1257
R
G
A
T
V
S
E
S
D
E
S
Q
W
P
E
Chicken
Gallus gallus
Q5F3U9
1412
161007
I1229
D
S
E
E
K
L
S
I
D
D
L
N
K
L
G
Frog
Xenopus laevis
Q5U241
1464
166906
A1257
G
R
K
R
A
A
A
A
S
E
S
E
E
Q
A
Zebra Danio
Brachydanio rerio
A1L1F4
1320
148940
V1143
Q
T
G
V
L
G
A
V
N
K
P
L
T
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610719
1218
138870
V1041
F
T
N
H
E
D
Y
V
Q
L
R
K
M
E
K
Honey Bee
Apis mellifera
XP_623860
1203
137941
C1026
Q
L
K
V
I
Q
Q
C
L
W
F
I
L
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790621
1624
181368
S1249
K
R
G
R
P
S
K
S
S
S
Q
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.3
88.4
N.A.
96.3
96.4
N.A.
94.4
91.4
84.4
63.9
N.A.
27.9
33.6
N.A.
40.3
Protein Similarity:
100
97.1
94.5
88.8
N.A.
97.7
97.7
N.A.
96.6
94.6
90.4
75.4
N.A.
46.5
52.3
N.A.
58.8
P-Site Identity:
100
100
100
100
N.A.
20
86.6
N.A.
13.3
0
20
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
40
93.3
N.A.
33.3
20
46.6
13.3
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
16
16
54
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
24
8
31
0
0
0
0
% D
% Glu:
0
0
8
8
8
0
8
0
39
24
8
47
8
16
16
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
16
16
39
0
8
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
8
39
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
8
39
16
0
8
0
8
0
0
8
0
8
8
0
8
% K
% Leu:
0
8
0
0
8
8
0
0
8
8
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
0
0
16
8
% P
% Gln:
16
0
0
0
0
8
8
0
8
0
16
16
39
47
0
% Q
% Arg:
54
16
47
16
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
0
24
8
62
16
47
16
8
8
8
8
% S
% Thr:
0
16
0
16
0
31
0
0
0
0
0
0
8
0
8
% T
% Val:
0
0
0
16
8
0
0
16
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
16
0
39
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _